TY - JOUR
T1 - Assessment of the roles of various inactivation agents in an argon-based direct current atmospheric pressure cold plasma jet
AU - Zhang, Qian
AU - Sun, Peng
AU - Feng, Hongqing
AU - Wang, Ruixue
AU - Liang, Yongdong
AU - Zhu, Weidong
AU - Becker, Kurt H.
AU - Zhang, Jue
AU - Fang, Jing
N1 - Funding Information:
This research is sponsored by Bioelectrics, Inc. (U.S.A.), Peking University Biomed-X Foundation and China International Science and Technology Cooperation (Grant No. 2009DFB30370). The authors would like to thank Yongsheng Cheng from Institute of Biophysics, Chinese Academy of Sciences, for his technical support in ESR spectroscopy, and thank Xiaodong Zhang, Xiaocheng Yang, and Xin Li from the Laboratory of Biomedical Signals and Image Studies at Peking University for their help in the development of CFU counting technique, and Hui Zhao from College of Environmental Sciences at Peking University for her technical support in [NO]/[NO] evaluation. 3 − 2 −
PY - 2012/6/15
Y1 - 2012/6/15
N2 - Three types of gases, pure argon (99.999), argon with 2 oxygen, and argon with 2 oxygen and 10 nitrogen were used as operating gases of a direct current atmospheric pressure cold plasma jet to inactivate Staphylococcus aureus (S. aureus) suspended in a liquid. The inactivation efficacies for the plasma jets operating in the three gases decrease from Ar/O 2(2) to Ar/O 2(2)/N 2(10) to pure Ar. Optical emission spectroscopy, electron spin resonance spectroscopy, high performance liquid chromatography, and atomic absorption spectrophotometry were employed to identify and monitor the reactive species in the plasma-liquid system for the three operating gases and revealed the presence of O, 1O 2, OH, NO, H 2O 2, O 3, and NO 3 -/NO 2 - as well as Cu +/Cu 2. The S. aureus inactivation results indicate that atomic oxygen (O) is the key inactivation agent, while other species play a lesser role in the inactivation progress studied here.
AB - Three types of gases, pure argon (99.999), argon with 2 oxygen, and argon with 2 oxygen and 10 nitrogen were used as operating gases of a direct current atmospheric pressure cold plasma jet to inactivate Staphylococcus aureus (S. aureus) suspended in a liquid. The inactivation efficacies for the plasma jets operating in the three gases decrease from Ar/O 2(2) to Ar/O 2(2)/N 2(10) to pure Ar. Optical emission spectroscopy, electron spin resonance spectroscopy, high performance liquid chromatography, and atomic absorption spectrophotometry were employed to identify and monitor the reactive species in the plasma-liquid system for the three operating gases and revealed the presence of O, 1O 2, OH, NO, H 2O 2, O 3, and NO 3 -/NO 2 - as well as Cu +/Cu 2. The S. aureus inactivation results indicate that atomic oxygen (O) is the key inactivation agent, while other species play a lesser role in the inactivation progress studied here.
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U2 - 10.1063/1.4730627
DO - 10.1063/1.4730627
M3 - Article
AN - SCOPUS:84863512333
SN - 0021-8979
VL - 111
JO - Journal of Applied Physics
JF - Journal of Applied Physics
IS - 12
M1 - 123305
ER -