Associations Between a Dopamine D4 Receptor Gene, Alcohol Use, and Sexual Behaviors Among Female Adolescent African Americans

Jessica M. Sales, Erica L. Smearman, Jennifer L. Brown, Gene H. Brody, Robert A. Philibert, Eve Rose, Ralph J. DiClemente

Research output: Contribution to journalArticle

Abstract

Young female adolescent African Americans are disproportionately impacted by HIV infection. There is a clear need to understand factors associated with increased HIV-risk behaviors among this vulnerable population. We sought to explore the association between a dopamine D4 receptor gene (DRD4), a genetic marker associated with natural variations in rewarding behaviors, and self-reported alcohol use and sexual risk behaviors, while controlling for other known correlates of risk-taking such as impulsivity, sensation-seeking, and peer norms, among a group of high-risk female adolescent African Americans to evaluate whether this biological factor enhances understanding of the patterns of risk in this vulnerable group.

Original languageEnglish (US)
Pages (from-to)136-153
Number of pages18
JournalJournal of HIV/AIDS and Social Services
Volume14
Issue number2
DOIs
StatePublished - Apr 3 2015

Keywords

  • African American
  • adolescents
  • risk-taking

ASJC Scopus subject areas

  • Health(social science)

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