@inproceedings{50f6028b738c4d248593cb59e17ff072,
title = "Atomic force microscopy for single cell analysis and mechanophenotyping of circulating tumor cells",
abstract = "Circulating tumor cells (CTCs) are attracting increasing interest in medical sciences as they play a key role to understanding cancer metastasis. The possibility to phenotype CTCs based on their physiological nature, biological responses, and defense mechanisms could open new venues for precision diagnosis, personalized treatments, and preventative measures. In this work, we employed Atomic Force Microscopy (AFM) for mechanophenotyping clinical prostate CTCs based on their measured elastic and adhesive properties. We performed the AFM force measurements on different cancer cell lines, namely MCF7 cells (breast cancer), LNCaP and PC3 cells (prostate cancer), and compared the results with clinical CTCs isolated from blood of prostate cancer patients.",
keywords = "AFM, CTCs, CellAdhesion, Diagnostics, Liquid Biopsy, Microfluidics, Phenotyping, Prostate, Viscoelasticity",
author = "Ayoub Glia and Muhammedin Deliorman and Qasaimeh, {Mohammad A.}",
note = "Publisher Copyright: {\textcopyright} 2020 IEEE.; 2020 International Conference on Manipulation, Automation, and Robotics at Small Scales, MARSS 2020 ; Conference date: 13-07-2020 Through 17-07-2020",
year = "2020",
month = jul,
day = "13",
doi = "10.1109/MARSS49294.2020.9307848",
language = "English (US)",
series = "Proceedings of MARSS 2020: International Conference on Manipulation, Automation, and Robotics at Small Scales",
publisher = "Institute of Electrical and Electronics Engineers Inc.",
editor = "Sinan Haliyo and Mokrane Boudaoud and Albert Sill and Sergej Fatikow",
booktitle = "Proceedings of MARSS 2020",
}