TY - JOUR
T1 - Auditory Hallucinations and Self-Injurious Behavior in General Population Adolescents
T2 - Modeling Within-Person Effects in the Tokyo Teen Cohort
AU - Stanyon, Daniel
AU - Devylder, Jordan
AU - Yamasaki, Syudo
AU - Yamaguchi, Satoshi
AU - Ando, Shuntaro
AU - Usami, Satoshi
AU - Endo, Kaori
AU - Miyashita, Mitsuhiro
AU - Kanata, Sho
AU - Morimoto, Yuko
AU - Hosozawa, Mariko
AU - Baba, Kaori
AU - Nakajima, Naomi
AU - Niimura, Junko
AU - Nakanishi, Miharu
AU - Hiraiwa-Hasegawa, Mariko
AU - Kasai, Kiyoto
AU - Nishida, Atsushi
N1 - Publisher Copyright:
© 2022 The Author(s).
PY - 2023/3/1
Y1 - 2023/3/1
N2 - Background and Hypotheses: A wealth of evidence suggests that adolescent psychotic experiences (PEs), and especially auditory hallucinations (AHs), are associated with an increased risk for self-injurious behavior (SIB). However, the directionality and specificity of this association are not well understood, and there are no published studies investigating within-person effects over time. The present study aimed to test whether AHs and SIB prospectively increase reciprocal risk at the individual level during early-to-middle adolescence. Study Design: Three waves (12y, 14y, and 16y) of self-reported AHs and SIB data from a large Tokyo-based adolescent birth cohort (N = 2825) were used. Random Intercept Cross-Lagged Panel Model (RI-CLPM) analysis was conducted to test the within-person prospective associations between AHs and SIB. Study Results: At the within-person level, AHs were associated with subsequent SIB over the observation period (12y-14y: β =. 118, P <. 001; 14-16y: β =. 086, P =. 012). The reverse SIB->AHs relationship was non-significant at 12-14y (β =. 047, P =. 112) but emerged from 14y to 16y as the primary direction of influence (β =. 243, P <. 001). Incorporating depression as a time-varying covariate did not meaningfully alter model estimates. Conclusions: A complex bi-directional pattern of relationships was observed between AHs and SIB over the measurement period, and these relationships were independent of depressive symptoms. Adolescent AHs may be both a predictor of later SIB and also a manifestation of SIB-induced psychological distress.
AB - Background and Hypotheses: A wealth of evidence suggests that adolescent psychotic experiences (PEs), and especially auditory hallucinations (AHs), are associated with an increased risk for self-injurious behavior (SIB). However, the directionality and specificity of this association are not well understood, and there are no published studies investigating within-person effects over time. The present study aimed to test whether AHs and SIB prospectively increase reciprocal risk at the individual level during early-to-middle adolescence. Study Design: Three waves (12y, 14y, and 16y) of self-reported AHs and SIB data from a large Tokyo-based adolescent birth cohort (N = 2825) were used. Random Intercept Cross-Lagged Panel Model (RI-CLPM) analysis was conducted to test the within-person prospective associations between AHs and SIB. Study Results: At the within-person level, AHs were associated with subsequent SIB over the observation period (12y-14y: β =. 118, P <. 001; 14-16y: β =. 086, P =. 012). The reverse SIB->AHs relationship was non-significant at 12-14y (β =. 047, P =. 112) but emerged from 14y to 16y as the primary direction of influence (β =. 243, P <. 001). Incorporating depression as a time-varying covariate did not meaningfully alter model estimates. Conclusions: A complex bi-directional pattern of relationships was observed between AHs and SIB over the measurement period, and these relationships were independent of depressive symptoms. Adolescent AHs may be both a predictor of later SIB and also a manifestation of SIB-induced psychological distress.
KW - RI-CLPM
KW - prospective cohort
KW - psychotic experiences
KW - psychotic symptoms
KW - self-harm
UR - http://www.scopus.com/inward/record.url?scp=85149417828&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85149417828&partnerID=8YFLogxK
U2 - 10.1093/schbul/sbac155
DO - 10.1093/schbul/sbac155
M3 - Article
C2 - 36333883
AN - SCOPUS:85149417828
SN - 0586-7614
VL - 49
SP - 329
EP - 338
JO - Schizophrenia bulletin
JF - Schizophrenia bulletin
IS - 2
ER -