Base-free palladium-catalyzed sonogashira coupling using organogold complexes

Sreekumar Pankajakshan, Teck Peng Loh

Research output: Contribution to journalArticlepeer-review

Abstract

Turn to gold: An effective protocol for base-free Sonogashira coupling reactions using organogold complexes as nucleophilic partners has been developed. The palladium-catalyzed methodology offers a general synthesis of aryl-alkynes under operationally simple conditions in good to excellent yields.

Original languageEnglish (US)
Pages (from-to)2291-2295
Number of pages5
JournalChemistry - An Asian Journal
Volume6
Issue number9
DOIs
StatePublished - Sep 5 2011

Keywords

  • alkynes
  • catalysis
  • cross-coupling
  • gold
  • palladium

ASJC Scopus subject areas

  • Biochemistry
  • Organic Chemistry

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