TY - JOUR
T1 - Baseline Hypothalamic–Pituitary–Adrenal Axis and Parasympathetic Nervous System Activity Interact to Predict Executive Functions in Low-Income Children
AU - Braren, Stephen H.
AU - Brandes-Aitken, Annie
AU - Perry, Rosemarie E.
AU - Williams, Kevon
AU - Lyons, Krystalle
AU - Rowe-Harriott, Sashana
AU - Blair, Clancy
N1 - Publisher Copyright:
© 2020 International Mind, Brain, and Education Society and Wiley Periodicals LLC
PY - 2021/2
Y1 - 2021/2
N2 - We examined interactions between baseline hypothalamic–pituitary–adrenal (HPA) axis and parasympathetic nervous system (PNS) activity in relation to executive functions (EF) in a sample (n = 1,005) of children in low wealth, nonurban communities at age 48 months. Salivary cortisol and respiratory sinus arrhythmia (RSA) represented baseline HPA axis and PNS activity, respectively. The interaction between RSA and cortisol predicted EF such that children with either lower RSA and lower cortisol, or higher RSA and higher cortisol had higher EF scores. These findings suggest a potential compensatory relation in which the PNS and HPA axis counterbalance each other to support cognition.
AB - We examined interactions between baseline hypothalamic–pituitary–adrenal (HPA) axis and parasympathetic nervous system (PNS) activity in relation to executive functions (EF) in a sample (n = 1,005) of children in low wealth, nonurban communities at age 48 months. Salivary cortisol and respiratory sinus arrhythmia (RSA) represented baseline HPA axis and PNS activity, respectively. The interaction between RSA and cortisol predicted EF such that children with either lower RSA and lower cortisol, or higher RSA and higher cortisol had higher EF scores. These findings suggest a potential compensatory relation in which the PNS and HPA axis counterbalance each other to support cognition.
UR - http://www.scopus.com/inward/record.url?scp=85096698726&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85096698726&partnerID=8YFLogxK
U2 - 10.1111/mbe.12267
DO - 10.1111/mbe.12267
M3 - Article
AN - SCOPUS:85096698726
SN - 1751-2271
VL - 15
SP - 61
EP - 66
JO - Mind, Brain, and Education
JF - Mind, Brain, and Education
IS - 1
ER -