Behavioral interventions for HIV infected and uninfected mothers with problem drinking

Marya V. Gwadz, Noelle R. Leonard, Charles M. Cleland, Marion Riedel, Gricel N. Arredondo, Hannah Wolfe, Emily Hardcastle, Jodi Morris

Research output: Contribution to journalArticlepeer-review


This article evaluates the efficacy of a 14-session social-cognitive behavioral intervention on problem drinking (and where applicable, drug use) among urban HIV-infected and uninfected mothers, in comparison to a single-session social/motivational intervention, and explores the relationships of initial substance use problem severity and HIV status to efficacy. A randomized controlled trial design was used. Participants (N = 118) were mothers with problem drinking, both HIV-infected (55%) and uninfected, and primarily from racial/ethnic minority and low socioeconomic status backgrounds. Participants were interviewed five times over 18 months. Both intervention arms yielded reductions in alcohol and drug use frequency, alcohol quantity, and alcohol/drug problems, with moderate effect sizes. Those with greater initial substance use maintained reductions over a longer period of time in response to the more intensive social-cognitive intervention. Treatment efficacy did not vary by HIV status. The utility of targeting intervention intensity to the level of substance use is supported.

Original languageEnglish (US)
Pages (from-to)47-65
Number of pages19
JournalAddiction Research and Theory
Issue number1
StatePublished - Feb 2008


  • Alcohol
  • Behavioral intervention
  • Drug use
  • HIV
  • Mothers
  • Motivational interviewing
  • Social-cognitive
  • Women

ASJC Scopus subject areas

  • Medicine (miscellaneous)


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