Bent into shape: Folded peptides to mimic protein structure and modulate protein function

Haley I. Merritt, Nicholas Sawyer, Paramjit S. Arora

Research output: Contribution to journalReview article

Abstract

Protein secondary and tertiary structure mimics have served as model systems to probe biophysical parameters that guide protein folding and as attractive reagents to modulate protein interactions. Here, we review contemporary methods to reproduce loop, helix, sheet, and coiled-coil conformations in short peptides.

Original languageEnglish (US)
Article numbere24145
JournalPeptide Science
Volume112
Issue number1
DOIs
StatePublished - Jan 1 2020

ASJC Scopus subject areas

  • Biophysics
  • Biochemistry
  • Biomaterials
  • Organic Chemistry

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