Bent into shape: Folded peptides to mimic protein structure and modulate protein function

Haley I. Merritt; Nicholas Sawyer; Paramjit S. Arora

doi:10.1002/pep2.24145

Bent into shape: Folded peptides to mimic protein structure and modulate protein function

Haley I. Merritt, Nicholas Sawyer, Paramjit S. Arora

Chemistry

Research output: Contribution to journal › Review article › peer-review

Abstract

Protein secondary and tertiary structure mimics have served as model systems to probe biophysical parameters that guide protein folding and as attractive reagents to modulate protein interactions. Here, we review contemporary methods to reproduce loop, helix, sheet, and coiled-coil conformations in short peptides.

Original language	English (US)
Article number	e24145
Journal	Peptide Science
Volume	112
Issue number	1
DOIs	https://doi.org/10.1002/pep2.24145
State	Published - Jan 1 2020

ASJC Scopus subject areas

Biophysics
Biochemistry
Biomaterials
Organic Chemistry

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title = "Bent into shape: Folded peptides to mimic protein structure and modulate protein function",

abstract = "Protein secondary and tertiary structure mimics have served as model systems to probe biophysical parameters that guide protein folding and as attractive reagents to modulate protein interactions. Here, we review contemporary methods to reproduce loop, helix, sheet, and coiled-coil conformations in short peptides.",

author = "Merritt, {Haley I.} and Nicholas Sawyer and Arora, {Paramjit S.}",

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T2 - Folded peptides to mimic protein structure and modulate protein function

AU - Merritt, Haley I.

AU - Sawyer, Nicholas

AU - Arora, Paramjit S.

PY - 2020/1/1

Y1 - 2020/1/1

N2 - Protein secondary and tertiary structure mimics have served as model systems to probe biophysical parameters that guide protein folding and as attractive reagents to modulate protein interactions. Here, we review contemporary methods to reproduce loop, helix, sheet, and coiled-coil conformations in short peptides.

AB - Protein secondary and tertiary structure mimics have served as model systems to probe biophysical parameters that guide protein folding and as attractive reagents to modulate protein interactions. Here, we review contemporary methods to reproduce loop, helix, sheet, and coiled-coil conformations in short peptides.

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DO - 10.1002/pep2.24145

M3 - Review article

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VL - 112

JO - Peptide Science

JF - Peptide Science

IS - 1

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Bent into shape: Folded peptides to mimic protein structure and modulate protein function

Abstract

ASJC Scopus subject areas

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