Bhc-diol as a photolabile protecting group for aldehydes and ketones

Min Lu, Olesya D. Fedoryak, Brent R. Moister, Timothy M. Dore

Research output: Contribution to journalArticlepeer-review

Abstract

(Matrix presented) 6-Bromo-4-(1,2-dihydroxyethyl)-7-hydroxycoumarin (Bhc-diol) can be used under simulated physiological conditions as a photoremovable protecting group for aldehydes and ketones. The single- and two-photon-induced release of benzaldehyde, piperonal, acetophenone, and cyclohexanone is demonstrated.

Original languageEnglish (US)
Pages (from-to)2119-2122
Number of pages4
JournalOrganic Letters
Volume5
Issue number12
DOIs
StatePublished - Jun 12 2003

ASJC Scopus subject areas

  • Biochemistry
  • Physical and Theoretical Chemistry
  • Organic Chemistry

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