Bilirubin in a new light

Johannes Broichhagen, Dirk Trauner

Research output: Contribution to journalReview article

Abstract

Green light for a new method: The protein UnaG shows bright green fluorescence in conjugation with bilirubin. The high affinity and specificity of UnaG allows for the fast and reliable measurement of bilirubin levels in human serum, which could improve the diagnosis of neonatal jaundice and other disorders based on insoluble bilirubin. UnaG expands the toolbox of fluorescent proteins with new features, such as oxygen independence and fast inducibility.

Original languageEnglish (US)
Pages (from-to)13868-13870
Number of pages3
JournalAngewandte Chemie - International Edition
Volume52
Issue number52
DOIs
StatePublished - Dec 23 2013

Keywords

  • bilirubin
  • fluorescence
  • genetic engineering
  • jaundice
  • proteins

ASJC Scopus subject areas

  • Catalysis
  • Chemistry(all)

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