Bio-chemical assay locking to thwart bio-IP theft

Sukanta Bhattacharjee; Jack Tang; Sudip Poddar; Mohamed Ibrahim; Ramesh Karri; Krishnendu Chakrabarty

doi:10.1145/3365579

Bio-chemical assay locking to thwart bio-IP theft

Sukanta Bhattacharjee, Jack Tang, Sudip Poddar, Mohamed Ibrahim, Ramesh Karri, Krishnendu Chakrabarty

Research output: Contribution to journal › Article

Abstract

It is expected that as digital microfluidic biochips (DMFBs) mature, the hardware design flow will begin to resemble the current practice in the semiconductor industry: design teams send chip layouts to third-party foundries for fabrication. These foundries are untrusted and threaten to steal valuable intellectual property (IP). In a DMFB, the IP consists of not only hardware layouts but also of the biochemical assays (bioassays) that are intended to be executed on-chip. DMFB designers therefore must defend these protocols against theft. We propose to “lock” biochemical assays by inserting dummy mix-split operations. We experimentally evaluate the proposed locking mechanism, and show how a high level of protection can be achieved even on bioassays with low complexity. We also demonstrate a new class of attacks that exploit the side-channel information to launch sophisticated attacks on the locked bioassay.

Original language	English (US)
Article number	5
Journal	ACM Transactions on Design Automation of Electronic Systems
Volume	25
Issue number	1
DOIs	https://doi.org/10.1145/3365579
State	Published - Dec 2019

Keywords

Bioassay
Digital microfluidic biochip
IP-theft
Locking

ASJC Scopus subject areas

Computer Science Applications
Computer Graphics and Computer-Aided Design
Electrical and Electronic Engineering

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Bhattacharjee, S., Tang, J., Poddar, S., Ibrahim, M., Karri, R., & Chakrabarty, K. (2019). Bio-chemical assay locking to thwart bio-IP theft. ACM Transactions on Design Automation of Electronic Systems, 25(1), [5]. https://doi.org/10.1145/3365579

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AU - Chakrabarty, Krishnendu

PY - 2019/12

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