Biochip-PUF: Physically Unclonable Function for Microfluidic Biochips

Navajit Singh Baban; Ajymurat Orozaliev; Yong Ak Song; Urbi Chatterjee; Sankalp Bose; Sukanta Bhattacharjee; Ramesh Karri; Krishnendu Chakrabarty

doi:10.1109/ITC51656.2023.00033

Biochip-PUF: Physically Unclonable Function for Microfluidic Biochips

Navajit Singh Baban, Ajymurat Orozaliev, Yong Ak Song, Urbi Chatterjee, Sankalp Bose, Sukanta Bhattacharjee, Ramesh Karri, Krishnendu Chakrabarty

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

Abstract

Flow-based microfluidic biochips (FMBs) have microvalves as key components. The physical characteristics of the microvalves vary instance-to-instance due to the inherent variability of numerous fabrication parameters. In this work, we leverage this unclonable, unpredictable instance-specific behavior and propose physically unclonable functions (PUFs) for FMBs, namely Biochip-PUFs (Bio-PUFs in short). We utilize variability in the microvalve membrane deflection response associated with the actuation pressure challenge to be our Bio-PUF parameter. Based on the distributions of the parameters measured on actual FMBs, we complement our Bio-PUF measurements via simulations of the FMB's microvalves in Comsol Multiphysics. Furthermore, we present a scheme based on the transient response of the microvalve actuation to augment the Bio-PUF authentication. The major advantage of this scheme is that we do not need any additional hardware to generate/implement the PUF module. The biochip itself can act as PUF instances while continuing to operate in normal functioning mode.

Original language	English (US)
Title of host publication	Proceedings - 2023 IEEE International Test Conference, ITC 2023
Publisher	Institute of Electrical and Electronics Engineers Inc.
Pages	166-175
Number of pages	10
ISBN (Electronic)	9798350343250
DOIs	https://doi.org/10.1109/ITC51656.2023.00033
State	Published - 2023
Event	2023 IEEE International Test Conference, ITC 2023 - Anaheim, United States Duration: Oct 7 2023 → Oct 15 2023

Publication series

Name	Proceedings - International Test Conference
ISSN (Print)	1089-3539

Conference

Conference	2023 IEEE International Test Conference, ITC 2023
Country/Territory	United States
City	Anaheim
Period	10/7/23 → 10/15/23

Keywords

Authentication
Biochips
Cyber-physical System
Intellectual Property
Microfluidics
Microvalves
Physically Unclonable Functions

ASJC Scopus subject areas

Electrical and Electronic Engineering
Applied Mathematics

Access to Document

10.1109/ITC51656.2023.00033

Cite this

Singh Baban, N., Orozaliev, A., Song, Y. A., Chatterjee, U., Bose, S., Bhattacharjee, S., Karri, R., & Chakrabarty, K. (2023). Biochip-PUF: Physically Unclonable Function for Microfluidic Biochips. In Proceedings - 2023 IEEE International Test Conference, ITC 2023 (pp. 166-175). (Proceedings - International Test Conference). Institute of Electrical and Electronics Engineers Inc.. https://doi.org/10.1109/ITC51656.2023.00033

Biochip-PUF: Physically Unclonable Function for Microfluidic Biochips. / Singh Baban, Navajit; Orozaliev, Ajymurat; Song, Yong Ak et al.
Proceedings - 2023 IEEE International Test Conference, ITC 2023. Institute of Electrical and Electronics Engineers Inc., 2023. p. 166-175 (Proceedings - International Test Conference).

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

Singh Baban, N, Orozaliev, A, Song, YA, Chatterjee, U, Bose, S, Bhattacharjee, S, Karri, R & Chakrabarty, K 2023, Biochip-PUF: Physically Unclonable Function for Microfluidic Biochips. in Proceedings - 2023 IEEE International Test Conference, ITC 2023. Proceedings - International Test Conference, Institute of Electrical and Electronics Engineers Inc., pp. 166-175, 2023 IEEE International Test Conference, ITC 2023, Anaheim, United States, 10/7/23. https://doi.org/10.1109/ITC51656.2023.00033

Singh Baban N, Orozaliev A, Song YA, Chatterjee U, Bose S, Bhattacharjee S et al. Biochip-PUF: Physically Unclonable Function for Microfluidic Biochips. In Proceedings - 2023 IEEE International Test Conference, ITC 2023. Institute of Electrical and Electronics Engineers Inc. 2023. p. 166-175. (Proceedings - International Test Conference). doi: 10.1109/ITC51656.2023.00033

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abstract = "Flow-based microfluidic biochips (FMBs) have microvalves as key components. The physical characteristics of the microvalves vary instance-to-instance due to the inherent variability of numerous fabrication parameters. In this work, we leverage this unclonable, unpredictable instance-specific behavior and propose physically unclonable functions (PUFs) for FMBs, namely Biochip-PUFs (Bio-PUFs in short). We utilize variability in the microvalve membrane deflection response associated with the actuation pressure challenge to be our Bio-PUF parameter. Based on the distributions of the parameters measured on actual FMBs, we complement our Bio-PUF measurements via simulations of the FMB's microvalves in Comsol Multiphysics. Furthermore, we present a scheme based on the transient response of the microvalve actuation to augment the Bio-PUF authentication. The major advantage of this scheme is that we do not need any additional hardware to generate/implement the PUF module. The biochip itself can act as PUF instances while continuing to operate in normal functioning mode.",

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AB - Flow-based microfluidic biochips (FMBs) have microvalves as key components. The physical characteristics of the microvalves vary instance-to-instance due to the inherent variability of numerous fabrication parameters. In this work, we leverage this unclonable, unpredictable instance-specific behavior and propose physically unclonable functions (PUFs) for FMBs, namely Biochip-PUFs (Bio-PUFs in short). We utilize variability in the microvalve membrane deflection response associated with the actuation pressure challenge to be our Bio-PUF parameter. Based on the distributions of the parameters measured on actual FMBs, we complement our Bio-PUF measurements via simulations of the FMB's microvalves in Comsol Multiphysics. Furthermore, we present a scheme based on the transient response of the microvalve actuation to augment the Bio-PUF authentication. The major advantage of this scheme is that we do not need any additional hardware to generate/implement the PUF module. The biochip itself can act as PUF instances while continuing to operate in normal functioning mode.

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Biochip-PUF: Physically Unclonable Function for Microfluidic Biochips

Abstract

Publication series

Conference

Keywords

ASJC Scopus subject areas

Access to Document

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