Bioluminescence tomography with a PDE-constrained algorithm based on the equation of radiative transfer

Hyun Keol Kim, Andreas H. Hielscher

    Research output: Chapter in Book/Report/Conference proceedingConference contribution

    Abstract

    We present the first bioluminescence tomography algorithm that makes use of the PDEconstrained concept, which has shown to lead to significant savings in computation times in similar applications. Implementing a sequential quadratic programming (SQP) method, we solve the forward and inverse problems simultaneously. Using numerical results we show that the PDEconstrained SQP approach leads to ~ 10 fold increase in convergence when compared to a standard unconstrained method.

    Original languageEnglish (US)
    Title of host publicationBiomedical Optics, BIOMED 2012
    PublisherOptical Society of America (OSA)
    PagesBSu3A.89
    ISBN (Print)9781557529428
    DOIs
    StatePublished - 2012
    EventBiomedical Optics, BIOMED 2012 - Miami, FL, United States
    Duration: Apr 28 2012May 2 2012

    Publication series

    NameBiomedical Optics, BIOMED 2012

    Conference

    ConferenceBiomedical Optics, BIOMED 2012
    CountryUnited States
    CityMiami, FL
    Period4/28/125/2/12

    ASJC Scopus subject areas

    • Biotechnology
    • Atomic and Molecular Physics, and Optics

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