Abstract
The aim of this study was to evaluate the biomechanical fixation, bone-to-implant contact, and bone morphology of an ion beam assisted deposition of a 300-500 nm thick Ca-and P-based bioceramic surface on a previously alumina-blasted/acid-etched Ti-6Al-4V implant surface in a dog model. Materials and Methods: Thirty-six 4.5 × 11 mm plateau root form implants, control (alumina-blasted/acid-etched-AB/AE) and test groups (AB/AE+300-500 nm bioceramic coating, Nanotite™) were placed along a proximal tibia of six beagle dogs remaining for 2 and 4 weeks (n = 3 animals per implantation time). Following euthanization, the implants were torqued to interface fracture at ∼0.196 radians/sec until a 10% maximum load drop was detected. The implants in bone were nondecalcified processed to ∼30 μm thickness slides for histomorphologic and bone-to-implant contact (BIC) assessment. Statistical analyses for torque to interface fracture were performed using a mixed model ANOVA, and BIC was evaluated by the χ2 test at 95% level of significance. Results: At 4 weeks, significantly higher torque to interface fracture was observed for the Test implant surface. Histomorphologic analysis showed higher degrees of bone organization for test implants compared to control at 2 and 4 weeks. Significantly higher BIC was observed at 4 weeks compared to 2 weeks (no statistical differences between control and test implants). Conclusion: The higher torque to interface fracture and increased bone maturity obtained in this study support that the surface modification comprising a 300-500 nm Ca- and P-based bioceramic coating positively influenced healing around pleateau root form implants.
Original language | English (US) |
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Pages (from-to) | 396-403 |
Number of pages | 8 |
Journal | Journal of Biomedical Materials Research - Part B Applied Biomaterials |
Volume | 90 |
Issue number | 1 |
DOIs | |
State | Published - Jul 2009 |
Keywords
- Dental implant
- Dogs
- Implant surface
- Thin coating
ASJC Scopus subject areas
- Biomaterials
- Biomedical Engineering