Biomimetic Synthesis of Complex Flavonoids Isolated from Daemonorops “Dragon's Blood”

Matthias Schmid, Dirk Trauner

Research output: Contribution to journalArticlepeer-review


The dragonbloodins are a pair of complex flavonoid trimers that have been isolated from the palm tree Daemonorops draco, one of the sources of the ancient resin known as “dragon's blood”. We present a short synthesis that clarifies their relative configurations and sheds light on their origin in Nature. This synthesis features biomimetic cascade reactions that involve both ionic and radical intermediates. The biogenetic relationships between dracorhodin, the dracoflavans C, and the dragonbloodins A1 and A2 are discussed.

Original languageEnglish (US)
Pages (from-to)12332-12335
Number of pages4
JournalAngewandte Chemie - International Edition
Issue number40
StatePublished - Sep 25 2017


  • autoxidation
  • biomimetic synthesis
  • cascade reactions
  • natural products
  • total synthesis

ASJC Scopus subject areas

  • Catalysis
  • General Chemistry


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