Abstract
The biomolecular modeling field has flourished since its early days in the 1970s due to the rapid adaptation and tailoring of state-of-the-art technology. The resulting dramatic increase in size and timespan of biomolecular simulations has outpaced Moore’s law. Here, we discuss the role of knowledge-based versus physics-based methods and hardware versus software advances in propelling the field forward. This rapid adaptation and outreach suggests a bright future for modeling, where theory, experimentation and simulation define three pillars needed to address future scientific and biomedical challenges.
Original language | English (US) |
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Pages (from-to) | 321-331 |
Number of pages | 11 |
Journal | Nature Computational Science |
Volume | 1 |
Issue number | 5 |
DOIs | |
State | Published - May 2021 |
ASJC Scopus subject areas
- Computer Science (miscellaneous)
- Computer Science Applications
- Computer Networks and Communications