TY - JOUR
T1 - Bisphosphonates and osteonecrosis of the jaw
T2 - Innocent association or significant risk?
AU - Carey, John J.
AU - Palomo, Leena
PY - 2008
Y1 - 2008
N2 - Published case series and systematic reviews have documented an association between bisphosphonates and osteonecrosis of the jaw. However, a cause-and-effect relationship has not been established, and most of the reported cases have been in patients with cancer who were receiving much higher doses than those used to treat osteoporosis or Paget disease of bone. The risk, if any, to patients with these latter conditions receiving these drugs appears to be very small.
AB - Published case series and systematic reviews have documented an association between bisphosphonates and osteonecrosis of the jaw. However, a cause-and-effect relationship has not been established, and most of the reported cases have been in patients with cancer who were receiving much higher doses than those used to treat osteoporosis or Paget disease of bone. The risk, if any, to patients with these latter conditions receiving these drugs appears to be very small.
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U2 - 10.3949/ccjm.75a.08014
DO - 10.3949/ccjm.75a.08014
M3 - Review article
C2 - 19088006
AN - SCOPUS:59849115834
SN - 0891-1150
VL - 75
SP - 871
EP - 878
JO - Cleveland Clinic Journal of Medicine
JF - Cleveland Clinic Journal of Medicine
IS - 12
ER -