Bleach use and HIV seroconversion among new york city injection drug users

Stephen Titus, Michael Marmor, Don Des Jarlais, Mimi Kim, Hannah Wolfe, Sara Beatrice

Research output: Contribution to journalArticlepeer-review


We employed a nested case-control study design to evaluate the efficacy of bleach-cleaning of needles and syringes among injecting drug users (IDUs) as a means of preventing human immunodeficiency virus (HIV) infection. Sixteen HIV-seroconverters who responded to bleach use questions and who reported injecting with shared or used equipment in the 6 months prior to their first positive visit were compared with 89 controls. Controls had remained HIV-seronegative at two or more visits, reported injecting with shared or used equipment, responded to bleach-cleaning questions, and were seen at recall visits ± 6 months from the date of seroconversion of the index case. Risk factors associated with HIV seroconversion in univariate analyses were a history of sexual intercourse with an HIV-infected partner and the frequency of speedball (mixed heroin and cocaine) injections. After adjusting for confounders, we found no evidence that bleach use protected against HIV infection.

Original languageEnglish (US)
Pages (from-to)700-704
Number of pages5
JournalJournal of Acquired Immune Deficiency Syndromes
Issue number7
StatePublished - Jul 1994


  • Disinfection
  • HIV seroconversion
  • Injection drug users
  • Prevention
  • Public health
  • Risk factors

ASJC Scopus subject areas

  • Infectious Diseases
  • Pharmacology (medical)


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