Abstract
The extension of the Bloch equations for acid-base reactions in an aqueous solution is revisited. The acid-base reactions are second order, and several reactions catalyzed by distinct catalysts may happen simultaneously. By constructing pseudo first-order reactions and assuming fast dissemination of protons from catalysts to solvent water, this extension converges to the well-known Bloch-McConnell equations for a two-site first-order exchange. Thus, explicit relationships between the parameters appearing in the reactions and the Bloch-McConnell equations are established. The dependencies of exchange rates and chemical exchange saturation transfer effects on pH were numerically and experimentally investigated for representative examples.
Original language | English (US) |
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Article number | e21397 |
Journal | Concepts in Magnetic Resonance Part A: Bridging Education and Research |
Volume | 45A |
Issue number | 3 |
DOIs | |
State | Published - May 2016 |
Keywords
- Bloch-McConnell equations
- acid-base reaction
- chemical exchange
- saturation transfer
ASJC Scopus subject areas
- Spectroscopy