Brachyury Locus

Research output: Chapter in Book/Report/Conference proceedingChapter


Brachyury is the first member to be identified of a family of evolutionarily conserved transcription factors that play major roles in development and disease in widely different organisms. Brachyury and the other T-box transcription factors are able to control gene expression by binding the regulatory regions of their target genes.

Original languageEnglish (US)
Title of host publicationBrenner's Encyclopedia of Genetics
Subtitle of host publicationSecond Edition
PublisherElsevier Inc.
Number of pages2
ISBN (Electronic)9780080961569
ISBN (Print)9780123749840
StatePublished - Feb 27 2013


  • Acromegaloid facial appearance syndrome
  • Brachyury
  • Chordoma
  • Cousin syndrome
  • DiGeorge syndrome
  • Holt-Oram syndrome
  • Notochord
  • Spina bifida
  • T-box
  • Transcription factor

ASJC Scopus subject areas

  • General Agricultural and Biological Sciences
  • General Biochemistry, Genetics and Molecular Biology
  • General Medicine


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