Brachyury Locus

A. Di Gregorio

doi:10.1016/B978-0-12-374984-0.00167-4

Brachyury Locus

A. Di Gregorio

Molecular Pathobiology

Research output: Chapter in Book/Report/Conference proceeding › Chapter

Abstract

Brachyury is the first member to be identified of a family of evolutionarily conserved transcription factors that play major roles in development and disease in widely different organisms. Brachyury and the other T-box transcription factors are able to control gene expression by binding the regulatory regions of their target genes.

Original language	English (US)
Title of host publication	Brenner's Encyclopedia of Genetics
Subtitle of host publication	Second Edition
Publisher	Elsevier Inc.
Pages	371-372
Number of pages	2
ISBN (Electronic)	9780080961569
ISBN (Print)	9780123749840
DOIs	https://doi.org/10.1016/B978-0-12-374984-0.00167-4
State	Published - Feb 27 2013

Keywords

Acromegaloid facial appearance syndrome
Brachyury
Chordoma
Cousin syndrome
DiGeorge syndrome
Holt-Oram syndrome
Notochord
Spina bifida
T-box
Transcription factor

ASJC Scopus subject areas

General Agricultural and Biological Sciences
General Biochemistry, Genetics and Molecular Biology
General Medicine

Access to Document

10.1016/B978-0-12-374984-0.00167-4

Cite this

@inbook{b6290be96b6b4059b2f065d6dd14c574,

title = "Brachyury Locus",

abstract = "Brachyury is the first member to be identified of a family of evolutionarily conserved transcription factors that play major roles in development and disease in widely different organisms. Brachyury and the other T-box transcription factors are able to control gene expression by binding the regulatory regions of their target genes.",

keywords = "Acromegaloid facial appearance syndrome, Brachyury, Chordoma, Cousin syndrome, DiGeorge syndrome, Holt-Oram syndrome, Notochord, Spina bifida, T-box, Transcription factor",

author = "{Di Gregorio}, A.",

year = "2013",

month = feb,

day = "27",

doi = "10.1016/B978-0-12-374984-0.00167-4",

language = "English (US)",

isbn = "9780123749840",

pages = "371--372",

booktitle = "Brenner's Encyclopedia of Genetics",

publisher = "Elsevier Inc.",

}

TY - CHAP

T1 - Brachyury Locus

AU - Di Gregorio, A.

PY - 2013/2/27

Y1 - 2013/2/27

N2 - Brachyury is the first member to be identified of a family of evolutionarily conserved transcription factors that play major roles in development and disease in widely different organisms. Brachyury and the other T-box transcription factors are able to control gene expression by binding the regulatory regions of their target genes.

AB - Brachyury is the first member to be identified of a family of evolutionarily conserved transcription factors that play major roles in development and disease in widely different organisms. Brachyury and the other T-box transcription factors are able to control gene expression by binding the regulatory regions of their target genes.

KW - Acromegaloid facial appearance syndrome

KW - Brachyury

KW - Chordoma

KW - Cousin syndrome

KW - DiGeorge syndrome

KW - Holt-Oram syndrome

KW - Notochord

KW - Spina bifida

KW - T-box

KW - Transcription factor

UR - http://www.scopus.com/inward/record.url?scp=85043230044&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85043230044&partnerID=8YFLogxK

U2 - 10.1016/B978-0-12-374984-0.00167-4

DO - 10.1016/B978-0-12-374984-0.00167-4

M3 - Chapter

AN - SCOPUS:85043230044

SN - 9780123749840

SP - 371

EP - 372

BT - Brenner's Encyclopedia of Genetics

PB - Elsevier Inc.

ER -

Brachyury Locus

Abstract

Keywords

ASJC Scopus subject areas

Access to Document

Other files and links

Fingerprint

Cite this