Brachyury Locus

Research output: Chapter in Book/Report/Conference proceedingChapter

Abstract

Brachyury is the first member to be identified of a family of evolutionarily conserved transcription factors that play major roles in development and disease in widely different organisms. Brachyury and the other T-box transcription factors are able to control gene expression by binding the regulatory regions of their target genes.

Original languageEnglish (US)
Title of host publicationBrenner's Encyclopedia of Genetics
Subtitle of host publicationSecond Edition
PublisherElsevier Inc.
Pages371-372
Number of pages2
ISBN (Electronic)9780080961569
ISBN (Print)9780123749840
DOIs
StatePublished - Feb 27 2013

Keywords

  • Acromegaloid facial appearance syndrome
  • Brachyury
  • Chordoma
  • Cousin syndrome
  • DiGeorge syndrome
  • Holt-Oram syndrome
  • Notochord
  • Spina bifida
  • T-box
  • Transcription factor

ASJC Scopus subject areas

  • Agricultural and Biological Sciences(all)
  • Biochemistry, Genetics and Molecular Biology(all)
  • Medicine(all)

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  • Cite this

    Di Gregorio, A. (2013). Brachyury Locus. In Brenner's Encyclopedia of Genetics: Second Edition (pp. 371-372). Elsevier Inc.. https://doi.org/10.1016/B978-0-12-374984-0.00167-4