Brain–Gut Axis: Clinical Implications

Julie Khlevner, Yeji Park, Kara Gross Margolis

Research output: Contribution to journalReview articlepeer-review

Abstract

This article provides an overarching view of what is currently known about the physiology of the brain–gut axis in both health and disease and how these concepts apply to irritable bowel syndrome, the most common functional gastrointestinal disorder in pediatrics.

Original languageEnglish (US)
Pages (from-to)727-739
Number of pages13
JournalGastroenterology Clinics of North America
Volume47
Issue number4
DOIs
StatePublished - Dec 2018

Keywords

  • Brain–gut axis
  • Brain–gut–microbiome axis
  • Enteric nervous system
  • Irritable bowel syndrome
  • Serotonin

ASJC Scopus subject areas

  • Gastroenterology

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