Brain–Gut Axis: Clinical Implications

Julie Khlevner, Yeji Park, Kara Gross Margolis

Research output: Contribution to journalReview articlepeer-review


This article provides an overarching view of what is currently known about the physiology of the brain–gut axis in both health and disease and how these concepts apply to irritable bowel syndrome, the most common functional gastrointestinal disorder in pediatrics.

Original languageEnglish (US)
Pages (from-to)727-739
Number of pages13
JournalGastroenterology Clinics of North America
Issue number4
StatePublished - Dec 2018


  • Brain–gut axis
  • Brain–gut–microbiome axis
  • Enteric nervous system
  • Irritable bowel syndrome
  • Serotonin

ASJC Scopus subject areas

  • Gastroenterology


Dive into the research topics of 'Brain–Gut Axis: Clinical Implications'. Together they form a unique fingerprint.

Cite this