Breast MRI at 7 Tesla with a bilateral coil and robust fat suppression

Ryan Brown, Pippa Storey, Christian Geppert, Kellyanne McGorty, Ana Paula Klautau Leite, James Babb, Daniel K. Sodickson, Graham C. Wiggins, Linda Moy

Research output: Contribution to journalArticlepeer-review


Purpose To develop a bilateral coil and fat suppressed T1-weighted sequence for 7 Tesla (T) breast MRI. Materials and Methods A dual-solenoid coil and three-dimensional (3D) T1w gradient echo sequence with B1+ insensitive fat suppression (FS) were developed. T1w FS image quality was characterized through image uniformity and fat-water contrast measurements in 11 subjects. Signal-to-noise ratio (SNR) and flip angle maps were acquired to assess the coil performance. Bilateral contrast-enhanced and unilateral high resolution (0.6 mm isotropic, 6.5 min acquisition time) imaging highlighted the 7T SNR advantage. Results Reliable and effective FS and high image quality was observed in all subjects at 7T, indicating that the custom coil and pulse sequence were insensitive to high-field obstacles such as variable tissue loading. 7T and 3T image uniformity was similar (P = 0.24), indicating adequate 7T B1+ uniformity. High 7T SNR and fat-water contrast enabled 0.6 mm isotropic imaging and visualization of a high level of fibroglandular tissue detail. Conclusion 7T T1w FS bilateral breast imaging is feasible with a custom radiofrequency (RF) coil and pulse sequence. Similar image uniformity was achieved at 7T and 3T, despite different RF field behavior and variable coil-tissue interaction due to anatomic differences that might be expected to alter magnetic field patterns. J. Magn. Reson. Imaging 2014;39:540-549. © 2013 Wiley Periodicals, Inc.

Original languageEnglish (US)
Pages (from-to)540-549
Number of pages10
JournalJournal of Magnetic Resonance Imaging
Issue number3
StatePublished - Mar 2014


  • RF coil
  • bilateral breast magnetic resonance imaging
  • breast cancer
  • fat suppression
  • high-field MRI

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging


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