Buspirone, a non‐benzodiazepine anxiolytic agent, produced a dose‐dependent decrease in the activity of 5‐HT‐containing dorsal raphe neurons recorded from mouse brain slices. The response was not changed in a low calcium/high magnesium incubation medium, indicating that the observed effects were the result of a direct action of buspirone on raphe neurons. These data are discussed within the context of the anxiolytic effects of buspirone.
|Original language||English (US)|
|Number of pages||3|
|Journal||Journal of Pharmacy and Pharmacology|
|State||Published - May 1986|
ASJC Scopus subject areas
- Pharmaceutical Science