Abstract
Buspirone, a non‐benzodiazepine anxiolytic agent, produced a dose‐dependent decrease in the activity of 5‐HT‐containing dorsal raphe neurons recorded from mouse brain slices. The response was not changed in a low calcium/high magnesium incubation medium, indicating that the observed effects were the result of a direct action of buspirone on raphe neurons. These data are discussed within the context of the anxiolytic effects of buspirone.
Original language | English (US) |
---|---|
Pages (from-to) | 380-382 |
Number of pages | 3 |
Journal | Journal of Pharmacy and Pharmacology |
Volume | 38 |
Issue number | 5 |
DOIs | |
State | Published - May 1986 |
ASJC Scopus subject areas
- General Medicine