Cannabinoids and viral infections

Research output: Contribution to journalReview article

Abstract

Exogenous cannabinoids or receptor antagonists may influence many cellular and systemic host responses. The anti-inflammatory activity of cannabinoids may compromise host inflammatory responses to acute viral infections, but may be beneficial in persistent infections. In neurons, where innate antiviral/pro-resolution responses include the activation of NOS-1, inhibition of Ca2+ activity by cannabinoids, increased viral replication and disease. This review examines the effect(s) of cannabinoids and their antagonists in viral infections.

Original languageEnglish (US)
Pages (from-to)1873-1886
Number of pages14
JournalPharmaceuticals
Volume3
Issue number6
DOIs
StatePublished - 2010

Keywords

  • Immunomodulation
  • Inflammation
  • Pathogens
  • Virus infection

ASJC Scopus subject areas

  • Molecular Medicine
  • Pharmaceutical Science

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