| Original language | English (US) |
|---|---|
| Pages (from-to) | 77-82 |
| Number of pages | 6 |
| Journal | Neurobiology of Aging |
| Volume | 8 |
| Issue number | 1 |
| DOIs | |
| State | Published - 1987 |
ASJC Scopus subject areas
- Neuroscience(all)
- Aging
- Clinical Neurology
- Developmental Biology
- Geriatrics and Gerontology
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In: Neurobiology of Aging, Vol. 8, No. 1, 1987, p. 77-82.
Research output: Contribution to journal › Article › peer-review
}
TY - JOUR
T1 - Cell and tissue transplantation into the adult brain
AU - Azmitia, Efrain C.
AU - Bjorklund, Anders
N1 - Funding Information: The first session dealt with interactions of neurons and glial cells and was chaired by Dr. Michael Shelanski from New York University. Dr. Alberto Aguayo (McGill University) spoke about his model of using peripheral nerve grafts to direct the growth of damaged CNS neurons. Data was presented that peripheral nerves could guide regenerating fibers of the eye from the retina to the superior colliculus. HRP was applied to the posterior chamber and time was allowed for the HRP to be anterogradely transported. The suspected terminals were then located with the electron microscope. Labeled profiles were identified but synaptic vesicle and post-synaptic profiles could not be identified. Nevertheless, it appeared clear that synaptic connectivity by HRP labeled profiles in the superior colliculus do occur. He remains the pioneer in the analysis of regenerative phenomenon because of his ability to isolate the various stages of the mechanism. Dr. Patricia Whitaker-Azmitia (SUNY at Stony Brook) discussed possible beneficial and deleterious effects of an astrocytic-scar which surrounds fetal transplants made into the adult brain. Reactive astrocytes could be identified using a GFAP antibody staining as early as 24 hr after a transplant of neural tissue into adult hippocampus. On the one hand, glial cells can provide neuronotrophic agents and surface adhesive molecules important for neuronal maturation and 1The meeting was sponsored by the New York Academy of Sciences and major support received from the National Institute of Mental Health, National Institute of Aging and U.S. Army. The sessions were held from April 2-4, 1986 at the Vista Hotel in New York City. Copyright: Copyright 2017 Elsevier B.V., All rights reserved.
PY - 1987
Y1 - 1987
UR - http://www.scopus.com/inward/record.url?scp=0023096084&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0023096084&partnerID=8YFLogxK
U2 - 10.1016/0197-4580(87)90062-5
DO - 10.1016/0197-4580(87)90062-5
M3 - Article
AN - SCOPUS:0023096084
SN - 0197-4580
VL - 8
SP - 77
EP - 82
JO - Neurobiology of Aging
JF - Neurobiology of Aging
IS - 1
ER -