Cell polarity: Tension quenches the rear

Alex Mogilner, Jie Zhu

Research output: Contribution to journalShort surveypeer-review


A combination of biophysical perturbations and computer simulations shows that leading edge protrusion in crawling cells increases membrane tension, which constrains the protruding front to one side of the cell, thereby maintaining its polarity.

Original languageEnglish (US)
Pages (from-to)R48-R51
JournalCurrent Biology
Issue number2
StatePublished - Jan 24 2012

ASJC Scopus subject areas

  • General Biochemistry, Genetics and Molecular Biology
  • General Agricultural and Biological Sciences


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