Cell polarity: Tension quenches the rear

Alex Mogilner; Jie Zhu

doi:10.1016/j.cub.2011.12.013

Cell polarity: Tension quenches the rear

Research output: Contribution to journal › Short survey › peer-review

Abstract

A combination of biophysical perturbations and computer simulations shows that leading edge protrusion in crawling cells increases membrane tension, which constrains the protruding front to one side of the cell, thereby maintaining its polarity.

Original language	English (US)
Pages (from-to)	R48-R51
Journal	Current Biology
Volume	22
Issue number	2
DOIs	https://doi.org/10.1016/j.cub.2011.12.013
State	Published - Jan 24 2012

ASJC Scopus subject areas

General Biochemistry, Genetics and Molecular Biology
General Agricultural and Biological Sciences

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10.1016/j.cub.2011.12.013

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title = "Cell polarity: Tension quenches the rear",

abstract = "A combination of biophysical perturbations and computer simulations shows that leading edge protrusion in crawling cells increases membrane tension, which constrains the protruding front to one side of the cell, thereby maintaining its polarity.",

author = "Alex Mogilner and Jie Zhu",

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AU - Zhu, Jie

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Cell polarity: Tension quenches the rear

Abstract

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