Cell polarity: Tension quenches the rear

Alex Mogilner, Jie Zhu

Research output: Contribution to journalShort survey

Abstract

A combination of biophysical perturbations and computer simulations shows that leading edge protrusion in crawling cells increases membrane tension, which constrains the protruding front to one side of the cell, thereby maintaining its polarity.

Original languageEnglish (US)
Pages (from-to)R48-R51
JournalCurrent Biology
Volume22
Issue number2
DOIs
StatePublished - Jan 24 2012

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)
  • Agricultural and Biological Sciences(all)

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