@article{a6a4ac4b66304fd8b64ec23c0bbe26dc,
title = "Cellular immune responses of mice to influenza virus infection",
abstract = "Mice infected with influenza virus develop cytotoxic T lymphocytes (CTL) specific for viral antigens prior to the appearance of virus-specific antibody-forming cells (AFCs). Effector T cells were detected at a time coincident with a precipitous decline in pulmonary virus titer. CTLs of draining lymph nodes and spleen were found to be cross-reactive among H-2 compatible cells infected with influenza type A virus subtypes. AFCs were observed to be primarily hemagglutinin specific. Virus-specific IgA-secreting AFCs were detected in mediastinal lymph nodes of infected mice.",
author = "Reiss, {Carol S.} and Schulman, {Jerome L.}",
note = "Funding Information: {\textquoteright} Supported in part by National Institutes of Health Grants AI 00439 and AI 09304. 2 Present address: Department of Pathology, Harvard Medical School, 25 Shattuck Street, Boston, Mass. 02115. 3 Abbreviations used: AFC, Antibody-forming cells; B/Lee virus, influenza B/Lee/40 virus; C3H, CeWStHa mouse strain; CML, cell-mediated lympholysis; CTL, cytotoxic T lymphocyte; EID,, 50% egg infectious dose; HA, hemagglutinin glycoprotein; HBSS, Hanks{\textquoteright} balanced salt solution; HI, hemagglutination inhibiting; Japan virus, influenza A/Japan/305/57 virus; MIDw, 50% mouse infectious dose; NA, neuraminidase glycoprotein; PR8 virus, influenza A/PR/8/34 virus; SIR, specific immune release; SRBC, sheep red blood cells.",
year = "1980",
month = dec,
doi = "10.1016/0008-8749(80)90124-0",
language = "English (US)",
volume = "56",
pages = "502--509",
journal = "Cellular Immunology",
issn = "0008-8749",
publisher = "Academic Press Inc.",
number = "2",
}