Challenges and opportunities for translating medical microdevices: Insights from the programmable bio-nano-chip

Michael P. McRae, Glennon Simmons, John T. McDevitt

Research output: Contribution to journalReview article

Abstract

This perspective highlights the major challenges for the bioanalytical community, in particular the area of lab-on-a-chip sensors, as they relate to point-of-care diagnostics. There is a strong need for general-purpose and universal biosensing platforms that can perform multiplexed and multiclass assays on real-world clinical samples. However, the adoption of novel lab-on-a-chip/microfluidic devices has been slow as several key challenges remain for the translation of these new devices to clinical practice. A pipeline of promising medical microdevice technologies will be made possible by addressing the challenges of integration, failure to compete with cost and performance of existing technologies, requisite for new content, and regulatory approval and clinical adoption.

Original languageEnglish (US)
Pages (from-to)905-919
Number of pages15
JournalBioanalysis
Volume8
Issue number9
DOIs
StatePublished - May 2016

Keywords

  • lab-on-a-chip
  • mHealth
  • microfluidic devices
  • point-of-care diagnostics
  • programmable bio-nano-chip (p-BNC)

ASJC Scopus subject areas

  • Analytical Chemistry
  • Pharmacology, Toxicology and Pharmaceutics(all)
  • Clinical Biochemistry
  • Medical Laboratory Technology

Fingerprint Dive into the research topics of 'Challenges and opportunities for translating medical microdevices: Insights from the programmable bio-nano-chip'. Together they form a unique fingerprint.

  • Cite this