Characterization and reversal of synaptic defects in the amygdala in a mouse model of fragile X syndrome

Neuroscience

• Amygdala 100%
• Fragile X Syndrome 100%
• Long-Term Potentiation 50%
• Excitatory Postsynaptic Potential 33%
• Hippocampus 16%
• Brain Slice 16%
• Synaptic Plasticity 16%
• Pervasive Developmental Disorder 16%
• Glutamate Receptor 16%
• AMPA Receptor 16%
• Receptor Subunit 16%
• NMDA Receptor 16%

Keyphrases

• MEPSCs 40%
• Metabotropic Glutamate Receptor 5 (mGluR5) 40%
• Phenylethynyl 40%
• Use-dependent Block 20%
• Current Frequency 20%
• Mental Impairment 20%
• Therapeutic Relevance 20%
• Brain Slice 20%
• Synaptic Release 20%
• Synaptic Function 20%
• Principal Neuron 20%
• Potential Therapeutics 20%
• NMDA Receptor Current 20%
• Emotional Symptoms 20%