Characterization of molecularly imprinted composite membranes using an atomic force microscope

Nidal Hilal, Victor Kochkodan, Laila Al-Khatib, Gerald Busca

Research output: Contribution to journalArticlepeer-review


Atomic force microscopy (AFM) has been used to investigate the surface structure of molecularly imprinted polyethersulphone (PES) membranes and to quantify pore size and surface roughness. Molecularly imprinted polymeric (MIP) membranes were developed using photoinitiated copolymerization of 2-hydroxyethyl methacrylate as functional monomer and trimethylopropane trimethacrylate as crosslinker in the presence of adenosine 3′:5″-cyclic monophosphate as template, followed by deposition of a MIP layer on the surface of (PES) microfiltration membranes. Atomic force microscopy images clearly indicate that a consistent increase in the degree of modification leads to a systematic decrease in pore size and an increase in surface roughness. These results show a good correlation with the filtration data of cAMP solutions. Thus, it was shown that direct AFM quantification of key parameters of imprinted membrane structure provide useful guidelines for the development of novel MIP composite membranes.

Original languageEnglish (US)
Pages (from-to)672-675
Number of pages4
JournalSurface and Interface Analysis
Issue number8
StatePublished - Aug 2002


  • Atomic force microscopy
  • Molecularly imprinted membranes
  • Pore size
  • Surface roughness

ASJC Scopus subject areas

  • General Chemistry
  • Condensed Matter Physics
  • Surfaces and Interfaces
  • Surfaces, Coatings and Films
  • Materials Chemistry


Dive into the research topics of 'Characterization of molecularly imprinted composite membranes using an atomic force microscope'. Together they form a unique fingerprint.

Cite this