Abstract
A number of contrast enhancement effects based on the use of intermolecular multiple-quantum coherences, or distant dipolar field effects are known. This phenomenon is characterized by the dependence on the mth power of the initial magnetization (where m is the coherence order used). In this paper, we describe the contrast enhancement based on chemical exchange saturation transfer and NOE, which is achieved by the use of intermolecular double-quantum coherences (iDQC). The method was validated using clinically relevant systems based on glycosaminoglycans and a sample of cartilage tissue, showing that the CEST contrast, as well as, NOE are enhanced by iDQC.
Original language | English (US) |
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Pages (from-to) | 29-32 |
Number of pages | 4 |
Journal | Journal of Magnetic Resonance |
Volume | 194 |
Issue number | 1 |
DOIs | |
State | Published - Sep 2008 |
Keywords
- CEST
- Chemical exchange saturation transfer
- DDF
- Distant dipolar field
- Intermolecular multiple-quantum coherences
- MRI
- Nonlinear dynamics
- iMQC
ASJC Scopus subject areas
- Biophysics
- Biochemistry
- Nuclear and High Energy Physics
- Condensed Matter Physics