Chiroptical Sensors

J. W. Canary, X. Duan, X. Liu

Research output: Chapter in Book/Report/Conference proceedingChapter


Chiroptical sensors play a very important role in detecting a wide range of analytes with a high level of sensitivity, responding not only to complexation-induced electronic effects but also changes in helicity and conformation of molecules and materials. Many scaffolds have been employed that respond to metal cations, small molecules, anions, and other analytes. This article describes the main scheme of chiroptical sensing and introduces various chiroptical sensors that are primarily based on circular dichroism spectroscopy. Several examples are highlighted to illustrate the progress in recent years.

Original languageEnglish (US)
Title of host publicationEncyclopedia of Spectroscopy and Spectrometry
PublisherElsevier Inc.
Number of pages8
ISBN (Print)9780128032244
StatePublished - 2017


  • Absolute configuration
  • Anion
  • Chiral analyte
  • Chirality
  • Chiroptical sensor
  • Circularly dichroism
  • Enantiomeric excess
  • Fluorescent sensing
  • Metal ion
  • Spectroscopy

ASJC Scopus subject areas

  • Instrumentation
  • Atomic and Molecular Physics, and Optics
  • Spectroscopy


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