Chromatin Proteins Do Double Duty

Sevinc Ercan, Jason D. Lieb

Research output: Contribution to journalShort surveypeer-review


The histone acetyltransferase MOF (males-absent-on-the-first) is required for the regulation of X chromosome gene dosage compensation in Drosophila males. In this issue, Kind et al. (2008) show that MOF is also found on autosomes and that it has two modes of binding: one in males for X chromosome dosage compensation and the other in both sexes for X chromosome and autosomal gene regulation independent of dosage compensation.

Original languageEnglish (US)
Pages (from-to)763-765
Number of pages3
Issue number5
StatePublished - May 30 2008

ASJC Scopus subject areas

  • General Biochemistry, Genetics and Molecular Biology


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