Chromatin Proteins Do Double Duty

Sevinc Ercan; Jason D. Lieb

doi:10.1016/j.cell.2008.05.011

Chromatin Proteins Do Double Duty

Sevinc Ercan, Jason D. Lieb

Biology and Genomics

Research output: Contribution to journal › Short survey › peer-review

Abstract

The histone acetyltransferase MOF (males-absent-on-the-first) is required for the regulation of X chromosome gene dosage compensation in Drosophila males. In this issue, Kind et al. (2008) show that MOF is also found on autosomes and that it has two modes of binding: one in males for X chromosome dosage compensation and the other in both sexes for X chromosome and autosomal gene regulation independent of dosage compensation.

Original language	English (US)
Pages (from-to)	763-765
Number of pages	3
Journal	Cell
Volume	133
Issue number	5
DOIs	https://doi.org/10.1016/j.cell.2008.05.011
State	Published - May 30 2008

ASJC Scopus subject areas

General Biochemistry, Genetics and Molecular Biology

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10.1016/j.cell.2008.05.011

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title = "Chromatin Proteins Do Double Duty",

abstract = "The histone acetyltransferase MOF (males-absent-on-the-first) is required for the regulation of X chromosome gene dosage compensation in Drosophila males. In this issue, Kind et al. (2008) show that MOF is also found on autosomes and that it has two modes of binding: one in males for X chromosome dosage compensation and the other in both sexes for X chromosome and autosomal gene regulation independent of dosage compensation.",

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AU - Lieb, Jason D.

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AB - The histone acetyltransferase MOF (males-absent-on-the-first) is required for the regulation of X chromosome gene dosage compensation in Drosophila males. In this issue, Kind et al. (2008) show that MOF is also found on autosomes and that it has two modes of binding: one in males for X chromosome dosage compensation and the other in both sexes for X chromosome and autosomal gene regulation independent of dosage compensation.

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JO - Cell

JF - Cell

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Chromatin Proteins Do Double Duty

Abstract

ASJC Scopus subject areas

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