Chronic oral mucosal ulceration in a 54-year-old female

Hsien Chiang, David A. Sirois, Leonard Bielory

Research output: Contribution to journalArticlepeer-review


Pemphigus vulgaris most often begins in the mouth but is often overlooked in the differential diagnosis of chronic multiple oral ulcerations and erosions. Accurate diagnosis requires perilesional biopsy including intact epithelium, submitted for hematoxylin and eosin as well as direct immunofluorescence staining. Early and aggressive treatment with moderate to high dose prednisone in combination with steroid sparing drugs such as azathioprine and mycophenolate allow complete remission in most patients.

Original languageEnglish (US)
Pages (from-to)391-395
Number of pages5
JournalAnnals of Allergy, Asthma and Immunology
Issue number4
StatePublished - Apr 2000

ASJC Scopus subject areas

  • Immunology and Allergy
  • Immunology
  • Pulmonary and Respiratory Medicine


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