Classification and experimental identification of plant long non-coding RNAs

Muneeza I. Rai; Maheen Alam; David A. Lightfoot; Priyatansh Gurha; Ahmed J. Afzal

doi:10.1016/j.ygeno.2018.04.014

Classification and experimental identification of plant long non-coding RNAs

Muneeza I. Rai, Maheen Alam, David A. Lightfoot, Priyatansh Gurha, Ahmed J. Afzal

Biology

Research output: Contribution to journal › Article › peer-review

Abstract

Our understanding of gene regulation is constantly evolving. It is now clear that the majority of cellular transcripts are non-coding RNAs. The spectrum of non-coding RNAs is diverse and includes short (<200 nt) and long non-coding RNAs (lncRNAs) (>200 nt). LncRNAs regulate gene expression through diverse mechanisms. In this review, we describe the emerging roles of lncRNA mediated plant gene regulation. We discuss the current classification of lncRNAs and their role in genome organization and gene regulation. We also highlight a subset of lncRNAs that are epigenetic regulators of plant gene expression. Lastly, we provide an overview of emerging techniques and databases that are employed for the identification and characterization of plant lncRNAs.

Original language	English (US)
Pages (from-to)	997-1005
Number of pages	9
Journal	Genomics
Volume	111
Issue number	5
DOIs	https://doi.org/10.1016/j.ygeno.2018.04.014
State	Published - Sep 2019

Keywords

Gene regulation
LncRNA
Non-coding RNA
RNA-seq

ASJC Scopus subject areas

Genetics

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10.1016/j.ygeno.2018.04.014

Cite this

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title = "Classification and experimental identification of plant long non-coding RNAs",

abstract = "Our understanding of gene regulation is constantly evolving. It is now clear that the majority of cellular transcripts are non-coding RNAs. The spectrum of non-coding RNAs is diverse and includes short (<200 nt) and long non-coding RNAs (lncRNAs) (>200 nt). LncRNAs regulate gene expression through diverse mechanisms. In this review, we describe the emerging roles of lncRNA mediated plant gene regulation. We discuss the current classification of lncRNAs and their role in genome organization and gene regulation. We also highlight a subset of lncRNAs that are epigenetic regulators of plant gene expression. Lastly, we provide an overview of emerging techniques and databases that are employed for the identification and characterization of plant lncRNAs.",

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AU - Rai, Muneeza I.

AU - Alam, Maheen

AU - Lightfoot, David A.

AU - Gurha, Priyatansh

AU - Afzal, Ahmed J.

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AB - Our understanding of gene regulation is constantly evolving. It is now clear that the majority of cellular transcripts are non-coding RNAs. The spectrum of non-coding RNAs is diverse and includes short (<200 nt) and long non-coding RNAs (lncRNAs) (>200 nt). LncRNAs regulate gene expression through diverse mechanisms. In this review, we describe the emerging roles of lncRNA mediated plant gene regulation. We discuss the current classification of lncRNAs and their role in genome organization and gene regulation. We also highlight a subset of lncRNAs that are epigenetic regulators of plant gene expression. Lastly, we provide an overview of emerging techniques and databases that are employed for the identification and characterization of plant lncRNAs.

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KW - Non-coding RNA

KW - RNA-seq

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Classification and experimental identification of plant long non-coding RNAs

Abstract

Keywords

ASJC Scopus subject areas

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