Classification of osseointegrated implant surfaces: Materials, chemistry and topography

David M. Dohan Ehrenfest, Paulo G. Coelho, Byung Soo Kang, Young Taeg Sul, Tomas Albrektsson

Research output: Contribution to journalReview articlepeer-review


Since the founding of the osseointegration concept, the characteristics of the interface between bone and implant, and possible ways to improve it, have been of particular interest in dental and orthopaedic implant research. Making use of standardized tools of analysis and terminology, we present here a standardized characterization code for osseointegrated implant surfaces. This code describes the chemical composition of the surface, that is, the core material, such as titanium, and its chemical or biochemical modification through impregnation or coating. This code also defines the physical surface features, at the micro- and nanoscale, such as microroughness, microporosity, nanoroughness, nanotubes, nanoparticles, nanopatterning and fractal architecture. This standardized classification system will allow to clarify unambiguously the identity of any given osseointegrated surface and help to identify the biological outcomes of each surface characteristic.

Original languageEnglish (US)
Pages (from-to)198-206
Number of pages9
JournalTrends in Biotechnology
Issue number4
StatePublished - Apr 2010

ASJC Scopus subject areas

  • Biotechnology
  • Bioengineering


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