Clinical, radiographic, and histologic study of endodontic treatment failures

Louis M. Lin, Elizeu A. Pascon, Joseph Skribner, Peter Gängler, Kaare Langeland

Research output: Contribution to journalArticlepeer-review


One hundred fifty cases of endodontic treatment failures were studied clinically, radiographically, and histologically. Fifty-seven percent of the teeth were asymptomatic. Pain alone and/or associated with swelling was present in 21% of the teeth. There was no correlation between the size of periradicular rarefaction and the occurrence or severity of clinical signs and/or symptoms. Stainable bacteria were demonstrated in 69% of the teeth and were present mostly in the canal. The severity of periradicular inflammation was related to presence of stainable bacteria in the canal. Swelling and pain or a draining sinus tract was often associated with stainable bacteria inside the canal. The development of a radicular cyst associated with an endodontically treated tooth that has failed is not necessarily the cause of endodontic treatment failure.

Original languageEnglish (US)
Pages (from-to)603-611
Number of pages9
JournalOral Surgery, Oral Medicine, Oral Pathology
Issue number5
StatePublished - May 1991

ASJC Scopus subject areas

  • Pathology and Forensic Medicine
  • General Dentistry


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