Clinical retinal imaging by high speed, ultrahigh resolution Spectral/Fourier domain optical coherence tomography

M. Wojtkowski, V. J. Srinivasan, T. H. Ko, J. S. Duker, J. S. Schuman, A. Kowalczyk, J. G. Fujimoto

Research output: Contribution to journalConference articlepeer-review


We present clinical data obtained with the aid of a novel instrumentation using, high speed, ultrahigh resolution Spectral/Fourier domain Optical Coherence Tomography (SOCT). This method allows performing video rate, ultrahigh resolution cross-sectional images with 98 dB of sensitivity, 100 times faster that previously reported UHR OCT system with comparable axial resolution of 3 um. Ultrahigh resolution imaging enables improved visualization of retinal architectural morphology compared to standard resolution OCT. High speed, ultrahigh resolution OCT using Spectral/Fourier domain detection promises to significantly enhance the utility of OCT for clinical applications. High speed imaging enables high density data sets to be acquired which can increase the quality of reconstructed cross-sectional images and can help to visualize small focal pathologic changes. This technique helps reconstructing true retinal topography without motion artifacts. Submitted manuscript describes the technology, its clinical performance and present preliminary data obtained for various retinal pathologies.

Original languageEnglish (US)
Article number18
Pages (from-to)84-89
Number of pages6
JournalProgress in Biomedical Optics and Imaging - Proceedings of SPIE
StatePublished - 2005
EventOphtalmic Technologies XV - San Jose, CA, United States
Duration: Jan 22 2005Jan 25 2005


  • Fourier-Domain OCT
  • Medical imaging
  • Ophthalmology
  • Optical Coherence Tomography

ASJC Scopus subject areas

  • Electronic, Optical and Magnetic Materials
  • Atomic and Molecular Physics, and Optics
  • Radiology Nuclear Medicine and imaging
  • Biomaterials


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