Participation des Afro-Américains aux essais cliniques et l’éthique de la confiance: perspectives de leadership

Translated title of the contribution: Clinical trials participation among African Americans and the ethics of trust: Leadership perspectives

R. C. Warren, M. G. Shedlin, E. Alema-Mensah, C. Obasaju, D. Augustin Hodge

Research output: Contribution to journalShort surveypeer-review

Abstract

Background: Assuring health equity throughout the US continues to challenge the public and private research enterprise. Even with some progress, racial and ethnic health disparities continue, particularly among African Americans. Health equity for African Americans is improbable unless participation in clinical trials is measurably increased. Method: To inform efforts to enhance participation, interviews were conducted with three African American leadership groups from across the country to document their perceptions of why the research community is unable to engage African Americans effectively in clinical trials. The results of thirty-five interviews, conducted from three leadership groups, were analyzed and are reported in this article. The leadership groups include health/education, faith, and civic society. Ethical considerations: This research was conducted based upon the ethical protocols of the National Center for Bioethics in Research and Health Care, research ethics, and confidentiality. Results: Findings indicate that trustworthiness must precede trust; both are essential in enhancing African American participation in research, especially in less understood clinical trials. Conclusion: Respondents agreed that the research community must demonstrate trustworthiness before trust can be established. They also indicated the importance of increasing the number of African American researchers in leadership roles. Also, suggestions were made regarding the need to develop short and long-term positive relationships between the research community and the African American population, at various levels, if increases in participation in clinical trials are expected. With the likely development of new clinical research and the attention to increasing excess deaths among African Americans, there must be representative numbers of African Americans and other underserved populations in leadership roles if health disparities are to be eliminated and health equity is to be achieved.

Translated title of the contributionClinical trials participation among African Americans and the ethics of trust: Leadership perspectives
Original languageFrench
Pages (from-to)128-138
Number of pages11
JournalEthics, Medicine and Public Health
Volume10
DOIs
StatePublished - Jul 1 2019

Keywords

  • African American
  • Bioethics
  • Clinical Trials
  • Ethics
  • Public Health
  • Trust
  • Trustworthiness

ASJC Scopus subject areas

  • Health Policy

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