Cofactor bypass variants reveal a conformational control mechanism governing cell wall polymerase activity

Biochemistry, Genetics and Molecular Biology

• Polymerase 100%
• Peptidoglycan 100%
• Outer Membrane 66%
• Escherichia coli 33%
• Conformational Change 33%
• Cell Membrane 33%
• Active Site 33%
• Synthase 33%
• Amino Acid Substitution 33%
• Inner Membrane 33%
• Lipoprotein 33%
• Glycosyltransferase 33%
• Penicillin Binding Protein 33%
• Penicillin 33%

Immunology and Microbiology

• Peptidoglycan 100%
• Cell Wall 100%
• Outer Membrane 66%
• Conformational Transition 33%
• Escherichia coli 33%
• Cell Membrane 33%
• Glycosyltransferase 33%
• Glycan 33%
• Amino Acid Substitution 33%
• Inner Membrane 33%
• Penicillin Binding Protein 33%
• Penicillin 33%

Keyphrases

• Polymerization Activity 28%
• Polymer Growth 14%
• Peptidoglycan Synthases 14%