TY - JOUR
T1 - Cognitive behavioral group therapy vs phenelzine therapy for social phobia 12-week outcome
AU - Heimberg, Richard G.
AU - Liebowitz, Michael R.
AU - Hope, Debra A.
AU - Schneier, Franklin R.
AU - Holt, Craig S.
AU - Welkowitz, Lawrence A.
AU - Juster, Harlan R.
AU - Campeas, Raphael
AU - Bruch, Monroe A.
AU - Cloitre, Marylene
AU - Fallon, Brian
AU - Klein, Donald F.
PY - 1998/12
Y1 - 1998/12
N2 - Background: This article presents results of the acute treatment phase of a 2-site study comparing cognitive behavioral group therapy (CBGT) and treatment with the monoamine oxidase inhibitor phenelzine sulfate for social phobia. Methods: One hundred thirty-three patients from 2 sites received 12 weeks of CBGT, phenelzine therapy, pill placebo administration, or educational-supportive group therapy (an attention-placebo treatment of equal credibility to CBGT). The 'allegiance effect,' ie, the tendency for treatments to seem most efficacious in settings of similar theoretical orientation and less efficacious in theoretically divergent settings, was also examined by comparing responses to the treatment conditions at both sites: 1 known for pharmacological treatment of anxiety disorders and the other for cognitive behavioral treatment. Results: After 12 weeks, phenelzine therapy and CBGT led to superior response rates and greater change on dimensional measures than did either control condition. However, response to phenelzine therapy was more evident after 6 weeks, and phenelzine therapy was also superior to CBGT after 12 weeks on some measures. There were few differences between sites, suggesting that these treatments can be efficacious at facilities with differing theoretical allegiances. Conclusions: After 12 weeks, both phenelzine therapy and CBGT were associated with marked positive response. Although phenelzine therapy was superior to CBGT on some measures, both were more efficacious than the control conditions. More extended cognitive behavioral treatment and the combination of modalities may enhance treatment effect.
AB - Background: This article presents results of the acute treatment phase of a 2-site study comparing cognitive behavioral group therapy (CBGT) and treatment with the monoamine oxidase inhibitor phenelzine sulfate for social phobia. Methods: One hundred thirty-three patients from 2 sites received 12 weeks of CBGT, phenelzine therapy, pill placebo administration, or educational-supportive group therapy (an attention-placebo treatment of equal credibility to CBGT). The 'allegiance effect,' ie, the tendency for treatments to seem most efficacious in settings of similar theoretical orientation and less efficacious in theoretically divergent settings, was also examined by comparing responses to the treatment conditions at both sites: 1 known for pharmacological treatment of anxiety disorders and the other for cognitive behavioral treatment. Results: After 12 weeks, phenelzine therapy and CBGT led to superior response rates and greater change on dimensional measures than did either control condition. However, response to phenelzine therapy was more evident after 6 weeks, and phenelzine therapy was also superior to CBGT after 12 weeks on some measures. There were few differences between sites, suggesting that these treatments can be efficacious at facilities with differing theoretical allegiances. Conclusions: After 12 weeks, both phenelzine therapy and CBGT were associated with marked positive response. Although phenelzine therapy was superior to CBGT on some measures, both were more efficacious than the control conditions. More extended cognitive behavioral treatment and the combination of modalities may enhance treatment effect.
UR - http://www.scopus.com/inward/record.url?scp=0031736386&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0031736386&partnerID=8YFLogxK
U2 - 10.1001/archpsyc.55.12.1133
DO - 10.1001/archpsyc.55.12.1133
M3 - Article
C2 - 9862558
AN - SCOPUS:0031736386
SN - 0003-990X
VL - 55
SP - 1133
EP - 1141
JO - Archives of General Psychiatry
JF - Archives of General Psychiatry
IS - 12
ER -