Common temporal identity factors regulate neuronal diversity in fly ventral nerve cord and mouse retina

Nikolaos Konstantinides, Anthony M. Rossi, Claude Desplan

Research output: Contribution to journalShort surveypeer-review

Abstract

Temporal sequences of transcription factors (tTFs) in Drosophila neural progenitors generate neuronal diversity. Mattar etal. (2015) identify Casz1/Castor as a late temporal identity factor in mouse retinal progenitors that is regulated by the early factor Ikzf1/Hunchback, thus generalizing the notion of tTFs. Temporal sequences of transcription factors (tTFs) in Drosophila neural progenitors generate neuronal diversity. Mattar etal. (2015) identify Casz1/Castor as a late temporal identity factor in mouse retinal progenitors that is regulated by the early factor Ikzf1/Hunchback, thus generalizing the notion of tTFs.

Original languageEnglish (US)
Pages (from-to)447-449
Number of pages3
JournalNeuron
Volume85
Issue number3
DOIs
StatePublished - Feb 4 2015

ASJC Scopus subject areas

  • Neuroscience(all)

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