Comparative cytotoxicity of poly(DTE carbonate) and poly(lactic acid)

S. R. Frenkel, J. R. Ricci, G. Chen

Research output: Contribution to conferencePaperpeer-review

Abstract

Cytotoxicity of poly(desaminotyrosyl-tyrosine ethyl ester carbonate) [poly(DTE carbonate)] and poly(lactic acid), and their long term degradation products was investigated. Results showed that only lactic acid, a degradation product of poly(lactic acid), was seriously toxic at concentrations of 0.1 mM and 1 mM. Poly(DTE carbonate) showed no evidence of cytotoxicity and allowed fibroblast cells to adhere and grow normally, making it a good candidate for a biodegradable implant material.

Original languageEnglish (US)
Pages271
Number of pages1
StatePublished - 1996
EventProceedings of the 1996 5th World Biomaterials Congress. Part 2 (of 2) - Toronto, Can
Duration: May 29 1996Jun 2 1996

Other

OtherProceedings of the 1996 5th World Biomaterials Congress. Part 2 (of 2)
CityToronto, Can
Period5/29/966/2/96

ASJC Scopus subject areas

  • Materials Science(all)

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