COMPARISON OF ANTIGEN EXTRACTED, LYOPHYLIZED AND GLUTARALDEHYDE FIXED BOVINE XENOGRAFT: A PRELIMINARY STUDY.

J. R. Parsons, J. C. Tauro, J. L. Ricci, H. Alexander, A. B. Weiss

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

In this study, bovine xenografts were treated with glutaraldehyde, lyophylized, or subjected to a chemical extraction procedure designed to remove antigenic cellular material and ground substance. Both the lyophylization and antigen extraction procedures produced graft material that initially is mechanically weaker than the glutaraldehyde-treated material. However, both of these treatments appear to yield a graft that supports much more rapid remodeling of graft and regrowth of host tissue than does glutaraldehyde treatment. Using a rabbit Achilles tendon repair model, the antigen extracted graft material has yielded promising results with excellent histologic and mechanical response.

Original languageEnglish (US)
Title of host publicationAdvances in Biomaterials
PublisherElsevier
Pages141-145
Number of pages5
ISBN (Print)0444426663
StatePublished - 1986

Publication series

NameAdvances in Biomaterials
ISSN (Print)0272-3840

ASJC Scopus subject areas

  • Engineering(all)

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