TY - GEN
T1 - COMPARISON OF ANTIGEN EXTRACTED, LYOPHYLIZED AND GLUTARALDEHYDE FIXED BOVINE XENOGRAFT
T2 - A PRELIMINARY STUDY.
AU - Parsons, J. R.
AU - Tauro, J. C.
AU - Ricci, J. L.
AU - Alexander, H.
AU - Weiss, A. B.
PY - 1986
Y1 - 1986
N2 - In this study, bovine xenografts were treated with glutaraldehyde, lyophylized, or subjected to a chemical extraction procedure designed to remove antigenic cellular material and ground substance. Both the lyophylization and antigen extraction procedures produced graft material that initially is mechanically weaker than the glutaraldehyde-treated material. However, both of these treatments appear to yield a graft that supports much more rapid remodeling of graft and regrowth of host tissue than does glutaraldehyde treatment. Using a rabbit Achilles tendon repair model, the antigen extracted graft material has yielded promising results with excellent histologic and mechanical response.
AB - In this study, bovine xenografts were treated with glutaraldehyde, lyophylized, or subjected to a chemical extraction procedure designed to remove antigenic cellular material and ground substance. Both the lyophylization and antigen extraction procedures produced graft material that initially is mechanically weaker than the glutaraldehyde-treated material. However, both of these treatments appear to yield a graft that supports much more rapid remodeling of graft and regrowth of host tissue than does glutaraldehyde treatment. Using a rabbit Achilles tendon repair model, the antigen extracted graft material has yielded promising results with excellent histologic and mechanical response.
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M3 - Conference contribution
AN - SCOPUS:0023014854
SN - 0444426663
T3 - Advances in Biomaterials
SP - 141
EP - 145
BT - Advances in Biomaterials
PB - Elsevier
ER -