TY - JOUR
T1 - Comparison of optic disc margin identified by color disc photography and high-speed ultrahigh-resolution optical coherence tomography
AU - Manassakorn, Anita
AU - Ishikawa, Hiroshi
AU - Kim, Jong S.
AU - Wollstein, Gadi
AU - Bilonick, Richard A.
AU - Kagemann, Larry
AU - Gabriele, Michelle L.
AU - Sung, Kyung Rim
AU - Mumcuoglu, Tarkan
AU - Duker, Jay S.
AU - Fujimoto, James G.
AU - Schuman, Joel S.
PY - 2008/1
Y1 - 2008/1
N2 - Objective: To determine the correspondence between optic disc margins evaluated using disc photography (DP) and optical coherence tomography (OCT). Methods: From May 1, 2005, through November 10, 2005, 17 healthy volunteers (17 eyes) had raster scans (180 frames, 501 samplings per frame) centered on the optic disc taken with stereo-optic DP and high-speed ultrahigh-resolution OCT (hsUHR-OCT). Two image outputs were derived from the hsUHR-OCT data set: an en face hsUHR-OCT fundus image and a set of 180 frames of cross-sectional images. Three ophthalmologists independently and in a masked, randomized fashion marked the disc margin on the DP, hsUHR-OCT fundus, and cross-sectional images using custom software. Disc size (area and horizontal and vertical diameters) and location of the geometric disc center were compared among the 3 types of images. Results: The hsUHR-OCT fundus image definition showed a significantly smaller disc size than the DP definition (P < .001, mixed-effects analysis). The hsUHR-OCT cross-sectional image definition showed a significantly larger disc size than the DP definition (P < .001). The geometric disc center location was similar among the 3 types of images except for the y-coordinate, which was significantly smaller in the hsUHR-OCT fundus images than in the DP images. Conclusion: The optic disc margin as defined by hsUHR-OCT was significantly different than the margin defined by DP.
AB - Objective: To determine the correspondence between optic disc margins evaluated using disc photography (DP) and optical coherence tomography (OCT). Methods: From May 1, 2005, through November 10, 2005, 17 healthy volunteers (17 eyes) had raster scans (180 frames, 501 samplings per frame) centered on the optic disc taken with stereo-optic DP and high-speed ultrahigh-resolution OCT (hsUHR-OCT). Two image outputs were derived from the hsUHR-OCT data set: an en face hsUHR-OCT fundus image and a set of 180 frames of cross-sectional images. Three ophthalmologists independently and in a masked, randomized fashion marked the disc margin on the DP, hsUHR-OCT fundus, and cross-sectional images using custom software. Disc size (area and horizontal and vertical diameters) and location of the geometric disc center were compared among the 3 types of images. Results: The hsUHR-OCT fundus image definition showed a significantly smaller disc size than the DP definition (P < .001, mixed-effects analysis). The hsUHR-OCT cross-sectional image definition showed a significantly larger disc size than the DP definition (P < .001). The geometric disc center location was similar among the 3 types of images except for the y-coordinate, which was significantly smaller in the hsUHR-OCT fundus images than in the DP images. Conclusion: The optic disc margin as defined by hsUHR-OCT was significantly different than the margin defined by DP.
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U2 - 10.1001/archophthalmol.2007.16
DO - 10.1001/archophthalmol.2007.16
M3 - Article
C2 - 18195219
AN - SCOPUS:38349050394
SN - 0003-9950
VL - 126
SP - 58
EP - 64
JO - Archives of Ophthalmology
JF - Archives of Ophthalmology
IS - 1
ER -