TY - JOUR
T1 - Comparison of oral fluid collectors for use in a rapid point-of-care diagnostic device
AU - Holm-Hansen, Carol
AU - Tong, Gary
AU - Davis, Cheryl
AU - Abrams, William R.
AU - Malamud, Daniel
PY - 2004/9
Y1 - 2004/9
N2 - Orally based diagnostic testing is emerging as an alternative, noninvasive method for analyzing a variety of analytes. These analytes include pathogens, antibodies, drugs, and nucleic acids. In the present study we developed a protocol for evaluation of collectors that could be used in orally based, point-of-care diagnostics. A performance comparison was carried out with a number of commercially available collectors, and their ability to deliver fluid, proteins, bacteria, and nucleic acid from pathogens compatible with PCR was assessed. The collectors were all capable of picking up and delivering test materials, albeit at various levels.
AB - Orally based diagnostic testing is emerging as an alternative, noninvasive method for analyzing a variety of analytes. These analytes include pathogens, antibodies, drugs, and nucleic acids. In the present study we developed a protocol for evaluation of collectors that could be used in orally based, point-of-care diagnostics. A performance comparison was carried out with a number of commercially available collectors, and their ability to deliver fluid, proteins, bacteria, and nucleic acid from pathogens compatible with PCR was assessed. The collectors were all capable of picking up and delivering test materials, albeit at various levels.
UR - http://www.scopus.com/inward/record.url?scp=4644221964&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=4644221964&partnerID=8YFLogxK
U2 - 10.1128/CDLI.11.5.909-912.2004
DO - 10.1128/CDLI.11.5.909-912.2004
M3 - Article
C2 - 15358651
AN - SCOPUS:4644221964
SN - 1071-412X
VL - 11
SP - 909
EP - 912
JO - Clinical and Diagnostic Laboratory Immunology
JF - Clinical and Diagnostic Laboratory Immunology
IS - 5
ER -