Complex Genomic Rearrangements following Selection in a Glutamine-Limited Medium over Hundreds of Generations

Pieter Spealman, Grace Avecilla, Julia Matthews, Ina Suresh, David Gresham

Research output: Contribution to journalArticlepeer-review

Abstract

Large-scale genomic changes, including copy number variations (CNVs), are frequently observed in long-term evolution experiments (LTEEs). We have previously reported the detection of recurrent CNVs in Saccharomyces cerevisiae populations adapting to glutamine-limited conditions over hundreds of generations. Here, we present the whole-genome sequencing (WGS) assemblies of 7 LTEE strains and their ancestor.

Original languageEnglish (US)
JournalMicrobiology Resource Announcements
Volume11
Issue number11
DOIs
StatePublished - Nov 2022

ASJC Scopus subject areas

  • Molecular Biology
  • Immunology and Microbiology (miscellaneous)
  • Genetics

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