Complex Genomic Rearrangements following Selection in a Glutamine-Limited Medium over Hundreds of Generations

Pieter Spealman; Grace Avecilla; Julia Matthews; Ina Suresh; David Gresham

doi:10.1128/mra.00729-22

Complex Genomic Rearrangements following Selection in a Glutamine-Limited Medium over Hundreds of Generations

Pieter Spealman, Grace Avecilla, Julia Matthews, Ina Suresh, David Gresham

Biology and Genomics

Research output: Contribution to journal › Article › peer-review

Abstract

Large-scale genomic changes, including copy number variations (CNVs), are frequently observed in long-term evolution experiments (LTEEs). We have previously reported the detection of recurrent CNVs in Saccharomyces cerevisiae populations adapting to glutamine-limited conditions over hundreds of generations. Here, we present the whole-genome sequencing (WGS) assemblies of 7 LTEE strains and their ancestor.

Original language	English (US)
Journal	Microbiology Resource Announcements
Volume	11
Issue number	11
DOIs	https://doi.org/10.1128/mra.00729-22
State	Published - Nov 2022

ASJC Scopus subject areas

Molecular Biology
Immunology and Microbiology (miscellaneous)
Genetics

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10.1128/mra.00729-22

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abstract = "Large-scale genomic changes, including copy number variations (CNVs), are frequently observed in long-term evolution experiments (LTEEs). We have previously reported the detection of recurrent CNVs in Saccharomyces cerevisiae populations adapting to glutamine-limited conditions over hundreds of generations. Here, we present the whole-genome sequencing (WGS) assemblies of 7 LTEE strains and their ancestor.",

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Complex Genomic Rearrangements following Selection in a Glutamine-Limited Medium over Hundreds of Generations

Abstract

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