Complexity and enumeration in models of genome rearrangement

Lora Bailey, Heather Smith Blake, Garner Cochran, Nathan Fox, Michael Levet, Reem Mahmoud, Elizabeth Bailey Matson, Inne Singgih, Grace Stadnyk, Xinyi Wang, Alexander Wiedemann

Research output: Contribution to journalArticlepeer-review

Abstract

In this paper, we examine the computational complexity of enumeration in certain genome rearrangement models. We first show that the PAIRWISE REARRANGEMENT problem in the Single Cut-and-Join model (Bergeron et al., 2010 [8]) is #P-complete under polynomial-time Turing reductions. Next, we show that in the Single Cut or Join model (Feijão and Meidanis, 2011 [21]), the problem of enumerating all medians ([Formula presented]) is logspace-computable (FL), improving upon the previous polynomial-time (FP) bound of Miklós & Smith [41].

Original languageEnglish (US)
Article number114880
JournalTheoretical Computer Science
Volume1022
DOIs
StatePublished - Dec 29 2024

ASJC Scopus subject areas

  • Theoretical Computer Science
  • General Computer Science

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