Computational Alanine Scanning with Interaction Entropy for Protein-Ligand Binding Free Energies

Biochemistry, Genetics and Molecular Biology

• Alanine 100%
• Ligand Binding 100%
• Protein Ligand 100%
• Wild Type 16%
• Binding Affinity 16%
• Quantitative Technique 16%
• Drug Resistance 16%
• Binding Energy 16%
• Drug Binding 16%

Chemistry

• Gibbs Free Energy 100%
• Alanine 100%
• Binding Energy 14%
• Kd 14%
• Molecular Dynamics 14%
• Free Energy of Binding 14%

Keyphrases

• Scanning Approach 20%
• Drug-protein Binding 20%
• Total Binding Energy 20%