Concise synthesis of (±)-smenochromene D (= likonide B)

Brooke S. Olson, Dirk Trauner

Research output: Contribution to journalArticlepeer-review


The total synthesis of smenochromene D, an unusual ansa-terpenoid is described. The synthesis features an unprecedented macrocyclization proceeding through a biomimetic electrocyclization. The enantiomeric relationship between smenochromene D and likonide B is established.

Original languageEnglish (US)
Pages (from-to)700-702
Number of pages3
Issue number4
StatePublished - Mar 4 2005


  • Ansa-compounds
  • Chromenes
  • Likonides
  • Macrocyclization
  • Ortho-quinone methides
  • Smenochromenes

ASJC Scopus subject areas

  • Organic Chemistry

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